Email - SC2Core@chla.usc.edu

Phone - (323) 361-8502 More...

Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents allow for a range of 1 million sequencing reads at the low end, and up a maximum of 25 million sequencing reads More...

The HiSeq System leverage innovative patterned flow cell technology to provide rapid, high-performance sequencing. Perform exome or transcriptome sequencing projects quickly and economically. More...

Chromium Single Cell Gene Expression provides single cell transcriptome 3' gene expression and multiomic capabilities to profile tens of thousands of cells. More...

Chromium Single Cell Immune Profiling provides a multiomic solution to your immunology questions. Analyze full-length, paired B-cell or T-cell receptors, surface protein expression, antigen specificity, and gene expression, all from a single cell. More...

Simultaneously profile gene expression and open chromatin from the same cell with Chromium Single Cell Multiome ATAC + Gene Expression. More...

Mass cytometry, CyTOF, is the world’s most advanced single-cell proteomics technology. It has opened new doors to discovery by empowering researchers to interrogate more than 50 markers simultaneously on millions of individual cells, to unveil new cell types, functions and biomarkers in immunology, cancer, stem cells and more. More...

Imaging Mass Cytometry (IMC) combines a precisely directed laser beam focused at 1 μm to collect biological samples stained with metal-tagged antibodies and directs these tags for analysis with proven CyTOF technology. Bringing together the high-multiplex capabilities of mass cytometry with imaging using metal-tagged antibodies allows simultaneous interrogation of 4 to 37 protein markers in tissues and tumors at subcellular resolution while preserving the information in tissue architecture and cell morphology.  More...

Visium Spatial Gene Expression is a next-generation molecular profiling solution for classifying tissue based on total mRNA. Map the whole transcriptome with morphological context in FFPE or fresh-frozen tissues to discover novel insights into normal development, disease pathology, and clinical translational research. More...

Our bioinformatics team provides all of the latest bioinformatics resources and expertise required to derive meaningful results from data generated on all ‘omics’ platforms. We have extensive experience with many popular software packages for single-cell RNA-seq (kallisto, Monocle2, DESeq2), metagenomics (QIIME, Kraken, MetaPhlAn2), and mass cytometry (Cytobank) analyses. We have access to private Linux servers as well as the USC High Performance Computing Core to provide you with all of the computing resources you may need regardless of the size of your project.  We provide a whole suite of services including analysis of experiments performed elsewhere. 

We also provide sizing, quantitation, and quality control of all of your samples using Agilent Bioanalyzer 2100.  More...

The Agilent 4200 TapeStation system is an established automated electrophoresis tool for DNA and RNA sample quality control.  More...

The Qubit 3.0 Fluorometer is for quantification of DNA and RNA molecules.

Return completed forms to Long Hung at lhung@chla.usc.edu More...

A web-based Core Management System that centralizes service and equipment scheduling, billing and usage tracking of CHLA’s nine centralized Core Facilities.

Click here for resources & job aids: CoreConnect SharePoint

The general Core Use Policy includes essential guidance on regulatory compliance, scheduling a service, equipment use, paying for Core services, and Core acknowledgement in publications. More...